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Thymos Health

Your drug bill
has an off switch.

A clinical program that helps autoimmune employees safely reduce — and eliminate — their biologic medications.

Thymos Health

For every 1,000 covered lives,
80 members are on an exponentially rising cost curve.

1
Three years of joint pain. Told it was stress, then aging, then anxiety. The fourth doctor said rheumatoid arthritis. She’d already stopped asking questions.
2
Crohn’s diagnosis came after an ER visit. He’s been on a biologic ever since. It helps, mostly. No one has ever suggested there might be another path.
3
She schedules her life around her flares. Some weeks she’s fine. Her chart says “well-controlled.” She doesn’t use that word.
$12K – $300K per person · per year · in prescription costs alone · after diagnosis · with no clinical off-ramp in sight
The Patient Before You

4.5 years. 4 specialists.
One snowball.

By the time a patient appears on your biologic spend report, they've been accumulating disease burden for years. Fragmented care, failed medications, and a growing risk that will cost your plan far more than the drug line.

Symptoms
begin
Yr 0
~$2K/yr
PCP visits
15 min · 4×/yr
Yr 1–4
~$4K/yr
4 specialists
still undiagnosed
Yr 2–3
~$14K/yr
Diagnosis
Biologic Rx
Yr 4.5
~$60K/yr
CVD + cancer
risk accruing
Yr 7.5
$150K+/yr
65%
of patients get no meaningful relief from their biologic — yet continue filling it indefinitely, hoping something will change
45%
begin accruing cardiovascular disease and cancer risk within 3 years of first symptoms — meaning most patients are already at risk before they're ever diagnosed
When Thymos intervenes, the snowball melts. Medication burden decreases. Downstream CVD and cancer risk follows. Your plan's long-term liability shrinks with it — before it ever compounds.
Active today
Biologic intervention
Yr 0
Yr 1–4
Yr 2–3
Yr 4.5 ←
Yr 7.5

Patient is already on a specialty biologic. Thymos assesses taper readiness, supports the clinical exit, and monitors for flare. The expensive drug stops. The savings start.

~$4,500 / month saved per tapered patient · avg $5K AWP − $500 program fee
Future capability
Claims + symptom triggered
Yr 0
Yr 1–4 ←
Yr 2–3
Yr 4.5
Yr 7.5

Thymos uses complex claims patterns and patient-reported symptom data to surface likely autoimmune patients before they're ever diagnosed — connecting them to care earlier and stopping the snowball before it has a chance to grow. The entire downstream cost curve never forms.

The whole snowball — avoided · earlier diagnosis, fewer specialists, no biologic escalation
Your population

What's happening
to your autoimmune members

Covered lives
Autoimmune est.
%
1,000
covered lives
→
80
autoimmune members · 8% of plan
Their costs begin long before they appear on a biologic claim.
~150–200
Yr 0
Symptoms begin
Meds · PCP visits · urgent care
~$2K/yr
~120–150
Yr 1–4
4 specialists · still undiagnosed
ER visits · failed meds · workups
~$14K/yr
~80
Yr 4.5
Diagnosis · Biologic Rx
$12K–$300K/yr · indefinite
 
Yr 7.5+
65% No meaningful relief — still on drug, still searching
35% Some relief — but side effects, still on drug
45% of your autoimmune members are slowly accumulating CVD + cancer risk — starting at first symptoms, years before diagnosis, before a biologic is ever prescribed
Est. annual specialty spend $2.0M
Adjust claims data ↓
Drug class GPI Fills/yr
your plan
AWP/fill Est. spend/yr
The Problem

No one is
guiding them off.

Biologics are prescribed for life — by default. Physicians manage flares. Nobody manages the exit.

✗
Diagnosis → biologic prescribed
Clinically appropriate. Often necessary. Usually indefinite.
✗
Symptoms improve — drug continues
There's no systematic trigger to revisit drug necessity once the patient is stable.
✗
Your plan pays. Every month. Forever.
$12,000–$300,000/year per patient. Indefinitely.
✗
"Just wait for the biosimilar."
Hadlima — Humira's biosimilar — lists around $1,000/month. Still $12,000/year. Still indefinite. Biosimilars cut the AWP; Thymos rightsizes their drug regimen while healing the patient.
What Thymos Does

Clinical support
for the taper path.

Thymos pairs autoimmune patients with clinicians who actively work toward reducing — and eventually eliminating — their biologic medication. Safely. Measurably.

🩺
Clinician-led program
Patients work with Thymos clinicians to stabilize symptoms and identify taper windows. Not just monitoring — active intervention.
📉
Measured by actual fills skipped
We track real pharmacy data: prescriptions available but not filled. That's the clinical signal and the cost signal — same metric.
🔒
De-identified to you
Employers receive monthly reports with aggregate and per-patient-code data. No names, no diagnoses. Just proof of savings.
The Economics

$500 to save
$1,000–$25,000 PMPM, indefinitely.

Every month a patient advances through the program, the cost asymmetry compounds.

$500 Thymos
$1,000 – $25,000 Biologic AWP
per patient · per month
Once the patient is off the biologic, $500–$24,500 net savings every month thereafter – even while the patient remains enrolled in Thymos.
Timeline to ROI

Patience is the
only input.

Tapering takes months. But every patient who engages pays back their full program cost — and then some.

0
Enrollment begins
Member receives outreach, opts in, begins working with Thymos clinician.
4
First fills skipped — early adopters
Some patients begin tapering at month 4. First measurable savings appear.
9
Most patients taper here
Typical taper window. Drug spend begins declining. Program paying for itself.
14
Expected cohort break-even
Cumulative savings surpass cumulative program cost.
18
Laggards taper — still net positive
Even slow adopters who taper at 18 months generate net gain within the 24-month commitment window.
24
Full payback confirmed
All engaged patients net-positive. Savings continue indefinitely as long as patients remain off biologics.

Based on 3-archetype model: early adopter (month 6), mid-cycle (month 12), slow adopter (month 18–19).

Your Group · 2-Year Model

10 participants.
$480K net gain.

Conservative estimate. $5K/month average biologic AWP.

Eligible members (8% of 1,000)
~80
Estimated on biologics
~40
Program participants (Year 1)
10
Program cost (24 months)
−$5K/mo · −$120K
Biologic fills avoided (conservative)
+$25K/mo · +$600K
2-Year Net Gain
≈ $20K/mo · ≈ $480K
Program
Cost
$5K/mo · $120K
Drug
Savings
$25K/mo · $600K
Net
Gain
$20K/mo · $480K

Assumes 10 program participants, avg biologic AWP $5K/mo, mixed engagement cohort (early/mid/late adopters). Actual PBM data will sharpen these numbers.

Per-patient trajectory · modeled 10-patient cohort

Three cost tiers, three adoption timings. Cards above show the blended average across early, mid, and late adopters for each tier. The higher the biologic cost, the more the ROI compounds — even at average engagement.

Low-cost tier · avg of early, mid & late
$1,000 / mo biologic
Avg break-even
M24
Avg net at M24
$0
Moderate tier · avg of early, mid & late
$5,000 / mo biologic
Avg break-even
M14
Avg net at M24
+$48,000
High-cost tier · avg of early, mid & late
$15,000 / mo biologic
Avg break-even
M13
Avg net at M24
+$168,000
Ultra-high tier · late adopter
$30,000 / mo biologic
Break-even
M19
Net at M24
+$168,000
Patient · Profile
M0 M3 M6 M9 M12 M15 M18 M21 M24
Before
w/ Thymos
Net
Patient 01
$1K/mo · Early (M6)
Onboard
Build Trust
Taper
Manage Flares
$24K
$18K
+$6K
Patient 02
$1K/mo · Mid (M12)
Onboard
Build Trust
Taper
Manage Flares
$24K
$24K
$0
Patient 03
$1K/mo · Late (M18)
Onboard
Build Trust
Taper
$24K
$30K
−$6K
Patient 04
$5K/mo · Early (M6)
Onboard
Build Trust
Taper
Manage Flares
$120K
$42K
+$78K
Patient 05
$5K/mo · Mid (M12)
Onboard
Build Trust
Taper
Manage Flares
$120K
$72K
+$48K
Patient 06
$5K/mo · Late (M18)
Onboard
Build Trust
Taper
$120K
$102K
+$18K
Patient 07
$15K/mo · Early (M6)
Onboard
Build Trust
Taper
Manage Flares
$360K
$102K
+$258K
Patient 08
$15K/mo · Mid (M12)
Onboard
Build Trust
Taper
Manage Flares
$360K
$192K
+$168K
Patient 09
$15K/mo · Late (M18)
Onboard
Build Trust
Taper
$360K
$282K
+$78K
Patient 10
$30K/mo · Late (M18)
Onboard
Build Trust
Taper
$720K
$552K
+$168K
Onboarding
Build Trust
Taper Therapy
Manage Flares
↓ Med decrease event
Break-even by M12
3 / 10
Pts 01, 04, 07 — early adopters
Break-even by M18
5 / 10
Pts 01, 04, 05, 07, 08
Net positive at M24
9 / 10
Only Pt 03 (low-cost, late) is negative
Cohort net at M24
+$816K
Across all 10 patients
How It Works

Four steps.
No disruption.

1
Believe the ROI
18–24 month investment appetite. The only gate.
2
Size your population
One email to your PBM. Thymos tells you what to ask for.
3
Introduce Thymos to members
Personalized letters to eligible members. Thymos follows up.
4
See the savings
Monthly report: fills skipped, AWP avoided, net gain.
Step 1 · Believe the ROI

The math is
straightforward.

$500/patient/month · 24-month commitment. One patient stopping a high-cost biologic pays for the whole program — and keeps paying, indefinitely.

Low-cost patient
$1K/mo biologic
Program cost−$12K
Drug savings+$20K
Net at 24mo+$8K
+$12K / yr · forever
Moderate-cost patient
$5K/mo biologic
Program cost−$12K
Drug savings+$75K
Net at 24mo+$63K
+$60K / yr · forever
High-cost patient
$25K/mo biologic
Program cost−$12K
Drug savings+$150K
Net at 24mo+$138K
+$300K / yr · forever
Once a patient stops their biologic, the savings recur every month, indefinitely. The 24-month window only shows the beginning of the return.
Step 2 · Size your population

One email.
Your eligibles — confirmed.

Thymos drafts the data request. You forward it to your health plan or PBM. They return a count — no PHI, no claims detail.

The request asks for
Members with ≥ 1 fill matching GPI list · last 12 months
Count per therapeutic class (TNF-α · IL-17/23 · IL-6 · JAK · Other)
Unique member count deduplicated across all classes
What comes back
A number. That's it. No names, no diagnoses.
If it's ≥ 10, the program is viable — and we size the ROI model from there.
View sample data request email →
Step 3 · Introduce Thymos to members

What each
member receives.

A personal letter from Thymos Health — voluntary, no-pressure, no clinical jargon. Members can call or go online to learn more.

The letter covers
What Thymos is · why it's being offered
Participation is voluntary with no impact on coverage
How to connect with a Thymos clinician
Thymos follows up directly
Where contact info is shared, Thymos calls the member — reducing the burden on your HR team to zero.
View member letter (direct outreach) → View HR benefit announcement →
Step 4 · See the savings

A report.
First week of every month.

De-identified. Actual fills. Cost math done for you. Pipeline, KPIs, therapeutic class breakdown — all in one page.

Participant Pipeline
40 targeted → 14 active → 7 tapering
This Month · April 2026
9 fills skipped
$46K AWP avoided
By Therapeutic Class
TNF-α · IL-17/IL-23 · IL-6 · Other
Fills expected vs. skipped, skip rate, AWP avoided per class
View sample report →
Next Step

Start with
your real numbers.

The model above uses industry averages. If you want to get more precise on your company's actual opportunity, one ask to your PBM is all it takes.

Request a PBM Data Pull
One ask to your health plan or PBM. Thymos does the rest — matching your claims to the target drug list and sizing your actual opportunity.
Let's size your opportunity →
Thymos Health
$500/participant/month · 24-month commitment · De-identified monthly reporting
Minimum viable cohort: 10–20 eligible members